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Study: Psoriasis Increases Stroke Risk


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Oct. 13, 2009

Psoriasis is typically viewed as a skin disorder. But emerging research suggests psoriasis puts people at greater risk for vascular diseases such as atherosclerosis and thrombosis.

Now, a population study published in October's Journal of Investigative Dermatology demonstrates psoriasis also raises patients' risk of stroke.

Psoriasis is a chronic Th-1 and Th-17 inflammatory disease. Researchers from the University of Pennsylvania conducted a population-based cohort study of psoriasis patients in the United Kingdom between 1987 to 2002. They compared these patients with a control group composed of people with no history of psoriasis.

After controlling for major risk factors for stroke, the researchers found psoriasis was indeed an independent risk factor for stroke. This risk increased for more severe psoriasis cases. They determined excess risk of stroke in patients with mild and severe psoriasis was 1 in 4,115 per year and 1 in 530 per year, respectively.

To read the abstract, click here.

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